A Mini Review: The Application of Eupatorium Plants as Potential Cosmetic Ingredients

(https://doi.org/10.3390/cosmetics9050103)

Agmi Sinta Putri, S.Si., M.Hut.

Abstract

The Eupatorium plant has been well used in medication and as a decorative plant. Some studies have reported that this herb has biochemical compounds, such as sesquiterpenes, phenolics, polysaccharides, and pyrrolizidine alkaloids. Thus, it has pharmacological effects, including antifungal, antibacterial, cytotoxic, and antinociceptive properties, that can be utilized for cosmetic purposes. However, only a few published works have summarized the active compounds and the application of Eupatorium plants as cosmetic agents. Therefore, this article aims to review the application of Eupatorium plants as a potential cosmetic agent. The active compounds of Eupatorium are contained in the whole plant, as well as the stems, leaves, roots, and aerial parts (flower, fruit, and seeds). In terms of cosmetic applications, the activities of Eupathorium are antioxidant, anti-tyrosinase, anti-melanin/melanogenesis, anti-acne, and anti-inflammatory. This review aims to contribute to a better understanding for expanding the utilization of this plant for cosmetic purposes by using these active compounds.

Pengujian Toksisitas Kulit Batang Kratom (Mitragyna speciosa Korth) Terhadap Larva Artemia salina 

Prof. Dr. R.R. Harlinda Kuspradini, S.Hut, MP.

Abstract

Toxicity, antioxidant ability and inhibition of oral pathogens by monoterpenerich essential oil of Litsea angulata Blume

Prof. Dr. R.R. Harlinda Kuspradini, S.Hut, MP.

Abstract

The genus Litsea comprises about 136 species worldwide and some species have been used in traditional medicine and as essential oil sources. Litsea angulata Blume is distributed throughout Indonesia, Malaysia and New Guinea. This study dealt with the chemical composition, toxicity, antioxidant and in vitro antimicrobial activities of essential oil from L. angulata leaves. The essential oil was produced using steam distillation and the chemical components of the oil were analyzed using gas chromatography-mass spectrometry (GC-MS). Inhibitory activity against oral pathogens (Staphylococcus aureus, Streptococcus mutans, Streptococcus sobrinus and Candida albicans) was assayed using the agar well diffusion method. Free radical scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) was used to analyze the antioxidant activity. The toxicity was evaluated using the in vivo brine shrimp lethality test (BSLT). GC-MS analysis revealed the presence of monoterpenoids (85.28%) and the major compounds were ?-pinene and cis-verbenol. The essential oil exhibited promising antimicrobial activity against the four test microorganisms, producing zones of inhibition with diameters of 11.44–50.00 mm. The highest inhibitory activity was obtained against S. mutans and S. sobrinus. The oil exhibited weak DPPH activity with 0–13.96% inhibition in the concentration range 0–50 µg/mL and was not toxic in the BSLT. These results demonstrated that this nontoxic essential oil could be considered as a potential antimicrobial agent against oral pathogens.

Minyak Atsiri Kayu Bawang. Pengolahan Daun Scorodarpus borneensis

Prof. Dr. R.R. Harlinda Kuspradini, S.Hut, MP.

Abstract